ST. PAUL, Minn – Call it a stroke of bad luck – a study published in the online edition of Neurology® has not brought very good news for middle aged women. Women are more prone to stroke during mid-life, as compared to men, thought to be due to expanding waist lines and heart disease.

For the study, researchers analyzed data from 17,000 people over the age of 18 who participated in the National Health and Nutrition Examination Survey. Of the participants, 606 people experienced a stroke.

The study found women in the 45 to 54 age range were more than twice as likely as men in the same age group to have had a stroke. There were no sex differences in stroke rates found in the 35 to 44 and the 55 to 64 age groups.

“While our analysis shows increased waist size and coronary artery disease are predictors of stroke among women aged 45 to 54, it is not immediately clear why there is a sex disparity in stroke rates among this age group,” said study author Amytis Towfighi, MD, with the Stroke Center and Department of Neurology at the University of California at Los Angeles, and member of the American Academy of Neurology. “While further study is needed, this mid-life stroke surge among women suggests prompt and close attention may need to be paid to the cardiovascular health of women in their mid-30s to mid-50s with a goal of mitigating this burden.”