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Child Brain Likely To Be Harmed By Stress

by Jyothsna on Mar 5 2007 12:18 PM

According to a latest study, increased levels of stress experienced by children may hamper their brain. This study reveals that in children suffering from post-traumatic stress disorder (PTSD), the component of the brain responsible for memory and emotion had become smaller in size. Chidlren finds it difficult to deal with stress and anxiety when their hippocampus is shrunken.

The children in the study also had higher blood levels of a stress hormone called cortisol, which has been shown to kill hippocampal cells in animals. The major question is whether the smaller hippocampus is a predictor of PTSD or a consequence Professor Joe Herbert, professor of neuroscience at Cambridge University.

This could set up a vicious cycle, where high cortisol causes more hippocampal damage, which in turn raises the anxiety. The Stanford University Medical Center scientists speculate that the ensuing damage could prolong the stress symptoms and also interfere with therapy. Lead researcher Victor Carrion explained: "One common treatment for PTSD is to help a sufferer develop a narrative of the traumatic experience. "But if the stress of the event is affecting areas of the brain responsible for processing information and incorporating it into a story, that treatment may not be as effective."

Extreme stress

He said stress had to be extreme to cause the damage. "We are not talking about the stress of doing your homework or fighting with your dad," Dr Carrion said. The 15 children he and his team studied all had PTSD as a result of physical, emotional or sexual abuse, witnessing violence or experiencing lasting separation and loss.

Dr Carrion said it would now be important to understand why some children appear to be more resilient to stress than others, and what the long-term effects of extreme stress are.

Experts already know a person's genes and environment play a role, and that having PTSD as a child increases the risk of depression and anxiety in adulthood.

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It is estimated that up to 1 in 10 people may develop PTSD at some stage in life. Professor Joe Herbert, professor of neuroscience at Cambridge University, said: "There is increasing evidence that adversity in early life can have long-lasting results on subsequent mental and physical health, and that at least some of these associations are the result of changes in the secretion of cortisol. "The major question is whether the smaller hippocampus is a predictor of PTSD or a consequence."

He said a study in war veterans with PTSD suggested a smaller hippocampus predisposes to PTSD, not the other way round.

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Source-Eurekalert
JYT


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