Acromegaly is a condition in adulthood due to excessive production of growth Hormone after puberty.

There exists a disease specially characterized by an hypertrophy of the hands, feet, and face, which we propose to call Acromegaly; that is to say, hypertrophy of the hands and feet "not because the hands and feet are alone affected during the course of the malady, but because their increase is an initial lesion, and constitutes the most characteristic feature of the affection".
Pierre Marie,1885